Written and medically reviewed by Dorcas Morak, PharmD
If you or someone you know is dealing with type 2 diabetes, you may have come across Mounjaro and Ozempic as potential medications. Both are used alongside diet and exercise to regulate blood sugar levels in adults with type 2 diabetes. However, there are some key differences between the two.Lowering A1C: Which Is Better?
Achieving and maintaining a healthy A1C level is crucial for managing diabetes and preventing complications. A study comparing Mounjaro and semaglutide (Ozempic) showed that Mounjaro is more effective in lowering A1C levels. Mounjaro resulted in reductions ranging from 2% to 2.3%, while the Ozempic group experienced a reduction of 1.9%. Additionally, Mounjaro led to greater weight loss compared to Ozempic.
Class of Drugs and Mechanisms of Action
Mounjaro and Ozempic both belong to the class of drugs called incretin mimetics, but they have some differences. Mounjaro acts on GIP and GLP-1 receptors, while Ozempic specifically targets GLP-1 receptors. Mounjaro contains tripeptide as the active ingredient, working as a dual-acting agonist. Ozempic contains semaglutide and acts as a GLP-1 receptor agonist.
Taking Mounjaro and Ozempic Together
It's important to note that you cannot take both Mounjaro and Ozempic simultaneously. You also cannot combine these medications with other GLP-1 or GLP receptor agonists. If you're not seeing the desired results with one medication, your doctor may adjust the dose or switch you to the other option.
Administration and Dosing
Both Mounjaro and Ozempic are administered as weekly subcutaneous injections using an injector pen. The recommended starting doses and maximum doses differ for each medication, and it's generally advised to start with the lower dose and gradually increase it to minimize potential side effects.
Switching Between Mounjaro and Ozempic
Mounjaro and Ozempic are not interchangeable due to differences in their mechanisms of action, indication, and dosing. Your healthcare provider will consider various factors, including your treatment goals, risk factors, and personal preferences, when determining which medication is more suitable for you. If a switch is necessary, your healthcare provider will guide you through the transition process.
Cost Comparison and Savings
The cost of Mounjaro and Ozempic can vary depending on factors such as your pharmacy, location, insurance coverage, and any available discounts or coupons. However, you can save on your prescription by using an RxLess discount coupon, which can help you save up to 88% at popular pharmacies like CVS, Rite Aid, and Walgreens.
Remember to consult with your healthcare provider to discuss the most appropriate medication for your specific needs and to address any concerns or questions you may have.
