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INSULIN ASPART; INSULIN ASPART PROTAMINE (IN su lin AS part; IN su lin AS part PRO ta meen) is a human-made form of insulin. This drug lowers the amount of sugar in your blood. This medicine is a mixture of a rapid-acting insulin and a longer-acting insulin. It starts working 10 to 20 minutes after injection and continues to work for as long as 12 to 24 hours.