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Generic: Dolutegravir, Rilpivirine Brand: JULUCA DOLUTEGRAVIR; RILPIVIRINE (doe loo teg ra veer; RIL pi VIR een) is 2 antiretroviral medicines in 1 tablet. It is used to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.