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Generic: Ibuprofen, Famotidine Brand: DUEXIS FAMOTIDINE; IBUPROFEN (fa MOE ti deen; eye BYOO proe fen) is two medicines together. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It is used for arthritis pain. Famotidine is a type of antihistamine that blocks the release of stomach acid. It is used to prevent stomach problems from the ibuprofen.