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Generic: Daratumumab, Hyaluronidase (Human recombinant) Brand: DARZALEX FASPRO DARATUMUMAB; HYALURONIDASE (dar a toom ue mab / hye al ur ON i dase) is a monoclonal antibody. Hyaluronidase is used to improve the effects of daratumumab. It treats certain types of cancer. Some of the cancers treated are multiple myeloma and light-chain amyloidosis.