Written and medically reviewed by Dorcas Morak, Pharm.D
Prescription medications play a vital role in managing chronic conditions like high blood pressure, diabetes, and heart disease. However, the cost of these medications can add up quickly, making affordability a significant concern for many people. If you take prescription medication regularly, your medication may be among the top 10 most commonly prescribed prescriptions in the U.S. Learn more about these medications and how to save on them.
What Are the Top 10 Most Prescribed Medications?
Each year, millions of Americans fill prescriptions for essential medications. Based on recent data, the following drugs are the most commonly prescribed in the U.S.:
- Atorvastatin (Lipitor) – A statin used to lower cholesterol and reduce the risk of heart disease.
- Metformin (Glucophage) – A first-line medication for type 2 diabetes that helps control blood sugar levels.
- Lisinopril (Zestril) – An ACE inhibitor that helps lower blood pressure and manage heart failure.
- Levothyroxine (Synthroid) – A thyroid hormone replacement used to treat hypothyroidism.
- Amlodipine (Norvasc) – A calcium channel blocker used to treat high blood pressure and chest pain.
- Metoprolol (Lopressor, Toprol XL) – A beta-blocker that treats high blood pressure, chest pain, and heart failure.
- Albuterol (Ventolin HFA, ProAir HFA) – A bronchodilator inhaler used for asthma and respiratory conditions.
- Losartan (Cozaar) – An angiotensin receptor blocker (ARB) used to treat high blood pressure and kidney disease in diabetic patients.
- Omeprazole (Prilosec) – A proton pump inhibitor (PPI) that treats acid reflux, GERD, and ulcers.
- Gabapentin (Neurontin) – A medication used for nerve pain, seizures, and sometimes off-label for anxiety or fibromyalgia.
How Do You Save Money on These Medications?
Use the RxLess™ Assurance Plan to Find the Best Prices One of the easiest ways to save on prescription medications is through the RxLess™ Assurance Plan. By downloading the free app, this plan ensures predictable and consistent savings on prescriptions, regardless of insurance status. Unlike traditional coupons, the RxLess™ Assurance Plan guarantees no hidden fees and upfront pricing transparency at participating pharmacies.
Opt for Generic Versions Most commonly prescribed medications have generic equivalents that offer the same effectiveness at a fraction of the cost. For example, atorvastatin (generic for Lipitor) and metformin (generic for Glucophage) are much cheaper alternatives. Always ask your doctor or pharmacist if a generic option is available.
Check Manufacturer Savings Programs Many pharmaceutical companies offer savings cards, rebates, or patient assistance programs for brand-name medications. For example, manufacturers of Ventolin HFA and Toprol XL often provide discount programs for eligible patients. Visit the manufacturer’s website to check for available savings options.
Compare Pharmacy Prices Prescription costs can vary significantly between pharmacies. The RxLess™ Assurance Plan helps you compare pharmacy prices and find the lowest-cost option in your area. For instance, omeprazole might cost significantly less at one pharmacy than another—using the RxLess™ platform ensures you always get the best discount.
Ask Your Doctor About Alternatives If your prescribed medication is expensive, ask your doctor about more affordable alternatives. Sometimes, another medication in the same class may be just as effective but significantly cheaper. For example, if you are prescribed losartan (Cozaar), your doctor may consider lisinopril as a lower-cost alternative.
What If You Can’t Afford Your Medication?
If you're struggling to afford your prescriptions, consider these additional options:
- Government Assistance Programs – Programs like Medicaid, Medicare Extra Help, and state pharmaceutical assistance programs provide financial relief for those who qualify.
- Nonprofit Assistance – Organizations such as the Healthwell Foundation and the PAN Foundation offer aid for individuals with high prescription costs.
Final Thoughts
Staying on top of your medications shouldn’t be a financial burden. By using the RxLess™ Assurance Plan, comparing prices, exploring manufacturer savings, and checking for generic alternatives, you can significantly lower your prescription costs. Taking the time to explore your options will help ensure you get the medications you need at the best possible price.
