Prescription Discount Pharmacies in Sioux Falls, South Dakota

The pharmacies below in Sioux Falls accept the RxLess® Assurance Plan.

Sioux Falls, South Dakota has 46 participating pharmacies, including Walgreens, Costco Pharmacy and Sams Pharmacy 10-8165 and more alongside local independents such as Sanford Cancer Center Oncology Clinic Pharmacy, Lewis Family Drug and Lewis Drug and more. Compare prices across all of them and save up to 88% with the RxLess® Assurance Plan

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Sanford Cancer Center Oncology Clinic Pharmacy
1309 W 17th St Ste 101
Sioux Falls, SD
(605) 328-8040

Mon-Fri (8:00am-5:00pm)

Sat-Sun (Closed)

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Lewis Family Drug
1205 S Grange Ave
Sioux Falls, SD
(605) 328-2620

Mon-Fri (8:00am-6:00pm)

Sat (9:00am-1:00pm)

Sun (Closed)

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Lewis Drug
136 S Phillips Ave
Sioux Falls, SD
(605) 367-2390

Mon-Fri (9:00am-6:00pm)

Sat-Sun (Closed)

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walgreens logo
1806 S Minnesota Ave
Sioux Falls, SD
(605) 221-0578

Mon-Sat (9:00am-6:00pm)

Sun (Closed)

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Lewis Drug
2700 W 12th St
Sioux Falls, SD
(605) 367-2210

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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walgreens logo
2605 W 12th St
Sioux Falls, SD
(605) 357-9359

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (Closed)

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Hy-Vee Pharmacy Fulfillment Center (4069)
2700 W 10TH ST STE 200
Sioux Falls, SD
(605) 330-8421

Call for hours

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Avera 7Th Avenue Pharmacy
1200 S 7th Ave Ste 101
Sioux Falls, SD
(605) 336-1816

Mon-Fri (8:30am-5:30pm)

Sat-Sun (Closed)

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Avera Mckennan Campus Pharmacy
1325 S Cliff Ave Ste Cp
Sioux Falls, SD
(605) 322-8326

Mon-Fri (8:00am-8:00pm)

Sat-Sun (9:00am-5:00pm)

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True Care Family Pharmacy
1120 E 10th St
Sioux Falls, SD
(605) 280-2601

Mon-Fri (9:00am-6:00pm)

Sat-Sun (Closed)

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Lewis Drug
1301 E 10th St
Sioux Falls, SD
(605) 367-2310

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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Avera Mckennan Home Infusion Therap
1020 S Cliff Ave
Sioux Falls, SD
(605) 322-8322

Mon-Fri (8:00am-5:00pm)

Sat-Sun (Closed)

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Avera Plaza 2 Pharmacy
1301 S CLIFF AVE STE 225
Sioux Falls, SD
(605) 322-8493

Mon-Fri (8:30am-5:00pm)

Sat-Sun (Closed)

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Avera Specialty Pharmacy
1301 S Cliff Ave Ste 200
Sioux Falls, SD
(605) 322-8300

Mon-Fri (8:00am-5:30pm)

Sat-Sun (Closed)

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Lewis Drug
2901 S Minnesota Ave
Sioux Falls, SD
(605) 367-2110

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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Hy-Vee Pharmacy
3000 S Minnesota Ave
Sioux Falls, SD
(605) 334-8012

Mon-Fri (8:00am-8:00pm)

Sat-Sun (9:00am-5:00pm)

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costco-wholesale logo
3700 S Grange Ave
Sioux Falls, SD
(605) 988-9150

Mon-Fri (10:00am-7:00pm)

Sat (9:30am-6:00pm)

Sun (Closed)

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Walmart Pharmacy
3209 S Louise Ave
Sioux Falls, SD
(605) 362-1602

Mon-Sat (9:00am-7:00pm)

Sun (10:00am-6:00pm)

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walgreens logo
3620 W 41st St
Sioux Falls, SD
(605) 361-5600

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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sams-club logo
3201 SOUTH LOUISE AVE
Sioux Falls, SD
(605) 362-2625

Mon-Fri (9:00am-7:00pm)

Sat (9:00am-6:00pm)

Sun (Closed)

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cvs logo
3600 S Louise Ave
Sioux Falls, SD
(605) 254-1100

Mon-Fri (9:00am-9:00pm)

Sat-Sun (9:00am-6:00pm)

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Hy-Vee Pharmacy
3020 E 10th St
Sioux Falls, SD
(605) 336-8998

Mon-Fri (8:00am-8:00pm)

Sat (9:00am-5:00pm)

Sun (10:00am-5:00pm)

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Hy-Vee Pharmacy
1900 S Marion Rd
Sioux Falls, SD
(605) 361-3347

Mon-Fri (8:00am-8:00pm)

Sat-Sun (9:00am-6:00pm)

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Hy-Vee Pharmacy
4101 S Louise Ave
Sioux Falls, SD
(605) 361-1382

Mon-Fri (8:00am-8:00pm)

Sat-Sun (9:00am-6:00pm)

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Pharmacy Specialties & Clinic Inc
2333 W 57th St Ste 109
Sioux Falls, SD
(605) 331-3190

Mon-Fri (8:30am-5:30pm)

Sat (10:00am-2:00pm)

Sun (Closed)

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Lewis Drug
5500 W 41st St
Sioux Falls, SD
(605) 367-2610

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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walgreens logo
4900 S Cliff Ave
Sioux Falls, SD
(605) 357-9233

Mon-Fri (9:00am-9:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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Hy-Vee Pharmacy
1231 E 57th St
Sioux Falls, SD
(605) 274-7062

Mon-Fri (8:00am-8:00pm)

Sat-Sun (9:00am-6:00pm)

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Lewis Drug
4409 E 26th St
Sioux Falls, SD
(605) 367-2710

Mon-Sun (8:00am-9:00pm)

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walgreens logo
1720 S Sycamore Ave
Sioux Falls, SD
(605) 221-0782

Mon-Fri (9:00am-9:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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Hy-Vee Pharmacy
1601 S Sycamore Ave
Sioux Falls, SD
(605) 334-1173

Mon-Fri (8:00am-8:00pm)

Sat (9:00am-5:00pm)

Sun (10:00am-5:00pm)

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Dan's Drugstore
5028 S Cliff Ave
Sioux Falls, SD
(605) 275-9442

Mon-Fri (8:00am-7:00pm)

Sat (8:00am-12:00pm)

Sun (Closed)

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Continued Care Ltc Pharmacy South Dakota Llc
4205 W 53RD ST STE 200
Sioux Falls, SD
(888) 277-2132

Mon-Fri (9:00am-5:00pm)

Sat (10:00am-2:00pm)

Sun (Closed)

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Walmart Pharmacy
7821 S Minnesota Ave
Sioux Falls, SD
(605) 338-9326

Mon-Sat (9:00am-7:00pm)

Sun (10:00am-6:00pm)

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Avera On Louise Pharmacy
6100 S Louise Ave Ste 1100
Sioux Falls, SD
(605) 322-8331

Mon-Fri (8:00am-5:00pm)

Sat-Sun (Closed)

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Avera Long Term Care Pharmacy
3820 N Potsdam Ave Ste 2
Sioux Falls, SD
(605) 322-1450

Mon-Fri (8:00am-6:00pm)

Sat-Sun (10:00am-2:00pm)

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Walmart Pharmacy
5521 E Arrowhead Pkwy
Sioux Falls, SD
(605) 367-3206

Mon-Sat (9:00am-7:00pm)

Sun (10:00am-6:00pm)

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Caretrends Pharmacy
6709 S Minnesota Ave Ste 105
Sioux Falls, SD
(605) 338-9383

Mon-Fri (8:30am-5:30pm)

Sat-Sun (Closed)

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Lewis Drug
6109 S Louise Ave
Sioux Falls, SD
(605) 367-2510

Mon-Fri (8:00am-9:00pm)

Sat (9:00am-9:00pm)

Sun (10:00am-9:00pm)

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walgreens logo
7120 W 41st St
Sioux Falls, SD
(605) 221-0989

Mon-Fri (9:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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Avera 69Th Street Pharmacy
4400 W 69th St Ste 300
Sioux Falls, SD
(605) 322-5948

Mon-Fri (9:00am-5:30pm)

Sat-Sun (Closed)

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Avera Dermatology Pharmacy
6701 S Minnesota Ave
Sioux Falls, SD
(605) 322-7695

Mon-Fri (8:00am-4:30pm)

Sat-Sun (Closed)

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cvs logo
1021 S Highline Pl
Sioux Falls, SD
(605) 333-5601

Mon-Fri (9:00am-7:00pm)

Sat (9:00am-5:00pm)

Sun (11:00am-5:00pm)

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Walmart Pharmacy
5200 W 60th St N
Sioux Falls, SD
(605) 906-6080

Mon-Sat (9:00am-7:00pm)

Sun (10:00am-6:00pm)

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Lewis Drug
2525 S Ellis Rd
Sioux Falls, SD
(605) 367-2410

Mon-Sun (8:00am-9:00pm)

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Lewis Drug
5830 E MADISON ST
Sioux Falls, SD
(605) 367-2010

Mon-Fri (8:00am-8:00pm)

Sat (9:00am-6:00pm)

Sun (10:00am-6:00pm)

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Frequently Asked Questions

Which pharmacies in Sioux Falls, South Dakota accept the RxLess® Assurance Plan?

46 pharmacies in Sioux Falls accept the RxLess® Assurance Plan. Browse the full list above to view their addresses, hours, and contact information.

How much can I save at Sioux Falls pharmacies with the RxLess® Assurance Plan?

RxLess® members can save up to 88% on prescription medications at participating pharmacies in Sioux Falls with the RxLess® Assurance Plan.

Do I need insurance to use the RxLess® marketplace in Sioux Falls?

No. The RxLess® Assurance Plan is a prescription savings card, not insurance. Anyone can use it, with or without insurance at participating pharmacies in Sioux Falls, South Dakota.

How do I use the RxLess® Assurance Plan at a Sioux Falls pharmacy?

Simply search for your medication in the RxLess® app, show the discount to a participating pharmacy in Sioux Falls, and pay the discounted price! It's that easy.